Treat with a concomitant medication. Using medications to manage antipsychotic side effects is a common but often suboptimal approach, because the beneficial effects of concomitant medications are often modest, they also may have adverse effects, and drug interactions may occur. For example, anticholinergic medications used to treat parkinsonism are associated with cognitive impairment and constipation. Further, few concomitant medication approaches are supported by evidence from randomized controlled trials.
Several antipsychotics are associated with significant weight gain, and virtually all antipsychotics are known to cause weight gain among youth3. Weight gain is among the most important antipsychotic side effects, because it is distressing to individuals and increases the risk of adverse health outcomes such as degenerative joint disease, type 2 diabetes mellitus and its complications, cardiovascular and cerebrovascular disease, as well as some types of cancer, and liver and kidney disease. Although weight gain commonly accompanies other adverse metabolic effects, adverse changes in lipids and insulin sensitivity may occur independently of weight gain3.
side effects may include happiness pdf 16
Anyone taking an antipsychotic medication should be regularly monitored for metabolic side effects. If these effects occur, lifestyle modifications are widely recommended and are a reasonable first step for individuals taking antipsychotic medications. Several structured behavioral programs have been tested and found effective in individuals with severe mental illnesses242, 243, 244, 245. Switching to an antipsychotic with lower risk for metabolic problems can be effective in helping individuals to lose weight and improve metabolic profiles4, 5.
Using these insights, one group that may be particularly important to consider is unemployed adults, who consistently have lower well-being than employed individuals. Previous research on unemployment and well-being has often focused on mental health problems among the unemployed [46] but there are also numerous studies of differences in positive aspects of well-being, mainly life satisfaction and happiness [22]. A large population-based study has demonstrated that unemployment is more strongly associated with the absence of positive well-being than with the presence of symptoms of psychological distress [28], suggesting that programs that aim to increase well-being among unemployed people may be more effective than programs that seek to reduce psychological distress.
Figure 7 complements those insights more specifically by showing how Finland and Norway, with a number of social, demographic, and economic similarities, plus identical life satisfaction scores (8.1) arrive at similar single MPWB scores with very different profiles for individual dimensions. By understanding the levers that are specific to each country (i.e. dimensions with the lowest well-being scores), policymakers can respond with appropriate interventions, thereby maximizing the potential for impact on entire populations. Had we restricted well-being measurement to a single question about happiness, as is commonly done, we would have seen both countries had similar and extremely high means for happiness. This might have led to the conclusion that there was minimal need for interventions for improving well-being. Thus, in isolation, using happiness as the single indicator would have masked the considerable variability on several other dimensions, especially those dimensions where one or both had means among the lowest of the 21 countries. This would have resulted in similar policy recommendations, when in fact, Norway may have been best served by, for example, targeting lower dimensions such as Engagement and Self-Esteem, and Finland best served by targeting Vitality and Emotional Stability.
One topic that could not be addressed directly is whether these measures offer value as indicators of well-being beyond the 21 countries included here, or even beyond the countries included in ESS generally. In other words, are these measures relevant only to a European population or is our approach to well-being measurement translatable to other regions and purposes? Broadly speaking, the development of these measures being based on DSM and ICD criteria should make them relevant beyond just the 21 countries, as those systems are generally intended to be global. However, it can certainly be argued that these methods for designing measures are heavily influenced by North American and European medical frameworks, which may limit their appropriateness if applied in other regions. Further research on these measures should consider this by adding potential further measures deemed culturally appropriate and seeing if comparable models appear as a result.
Naturally, it is not a compelling argument to simply state that more measures present greater information than fewer or single measures, and this is not the primary argument of this manuscript. In many instances, national measures of well-being are mandated to be restricted to a limited set of items. What is instead being argued is that well-being itself is a multidimensional construct, and if it is deemed a critical insight for establishing policy agenda or evaluating outcomes, measurements must follow suit and not treat happiness and life satisfaction values as universally indicative. The items included in ESS present a very useful step to that end, even in a context where the number of items is limited.
People respond to antipsychotic medications in different ways. It is important to report any side effects to a health care provider. Many people taking antipsychotic medications experience side effects such as weight gain, dry mouth, restlessness, and drowsiness when they start taking these medications. Some of these side effects may go away over time, while others may last.
Everyone's different, so finding the right medication or dose for your teen may take some trial and error. This requires patience, as some medications need several weeks or longer to take full effect and for side effects to ease as the body adjusts. Encourage your teen not to give up.
Cocaine (from French: cocaïne, from Spanish: coca, ultimately from Quechua: kúka)[14] is a central nervous system (CNS) stimulant. As an extract it is mainly used recreationally and often illegally for its euphoric effects, but it is Schedule II in the U.S. and recognized for its medical value. It is primarily obtained from the leaves of two Coca species native to South America: Erythroxylum coca and E. novogranatense.[15][16] These medicinal herbs naturally contain cocaine and have a history of use among indigenous American peoples. After extraction from the plant, and further processing into cocaine hydrochloride (powdered cocaine), the drug is administered by being either snorted, applied topically to the mouth, or dissolved and injected into a vein. It can also then be turned into free base form (crack cocaine), in which it can be heated until sublimated and then the vapours can be inhaled.[12] Cocaine stimulates the reward pathway in the brain.[16] Mental effects may include an intense feeling of happiness, sexual arousal, loss of contact with reality, or agitation.[12] Physical effects may include a fast heart rate, sweating, and dilated pupils.[12] High doses can result in high blood pressure or high body temperature.[17] Effects begin within seconds to minutes of use and last between five and ninety minutes.[12] As cocaine also has numbing and blood vessel constriction properties, it is occasionally used during surgery on the throat or inside of the nose to control pain, bleeding, and vocal cord spasm.[18]
Subjective effects not commonly shared with other methods of administration include a ringing in the ears moments after injection (usually when over 120 milligrams) lasting two to 5 minutes including tinnitus and audio distortion. This is colloquially referred to as a "bell ringer". In a study of cocaine users, the average time taken to reach peak subjective effects was 3.1 minutes.[53] The euphoria passes quickly. Aside from the toxic effects of cocaine, there is also the danger of circulatory emboli from the insoluble substances that may be used to cut the drug. As with all injected illicit substances, there is a risk of the user contracting blood-borne infections if sterile injecting equipment is not available or used.
Physical side effects from chronic smoking of cocaine include coughing up blood, bronchospasm, itching, fever, diffuse alveolar infiltrates without effusions, pulmonary and systemic eosinophilia, chest pain, lung trauma, sore throat, asthma, hoarse voice, dyspnea (shortness of breath), and an aching, flu-like syndrome. Cocaine constricts blood vessels, dilates pupils, and increases body temperature, heart rate, and blood pressure. It can also cause headaches and gastrointestinal complications such as abdominal pain and nausea. A common but untrue belief is that the smoking of cocaine chemically breaks down tooth enamel and causes tooth decay. Cocaine can cause involuntary tooth grinding, known as bruxism, which can deteriorate tooth enamel and lead to gingivitis.[80] Additionally, stimulants like cocaine, methamphetamine, and even caffeine cause dehydration and dry mouth. Since saliva is an important mechanism in maintaining one's oral pH level, people who use cocaine over a long period of time who do not hydrate sufficiently may experience demineralization of their teeth due to the pH of the tooth surface dropping too low (below 5.5). Cocaine use also promotes the formation of blood clots.[12] This increase in blood clot formation is attributed to cocaine-associated increases in the activity of plasminogen activator inhibitor, and an increase in the number, activation, and aggregation of platelets.[12]
Crack baby is a term for a child born to a mother who used crack cocaine during her pregnancy. The threat that cocaine use during pregnancy poses to the fetus is now considered exaggerated.[96] Studies show that prenatal cocaine exposure (independent of other effects such as, for example, alcohol, tobacco, or physical environment) has no appreciable effect on childhood growth and development.[97]However, the official opinion of the National Institute on Drug Abuse of the United States warns about health risks while cautioning against stereotyping: 2ff7e9595c
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